Thursday, January 31, 2013

Fourth grader wins science fair with drug-sniffing dogs, ounce of cocaine

A detective provided his daughter with drug-sniffing dogs, like this one, and cocaine for a science fair. (Get??

In an early bid for Father of the Year, a Miami police detective allowed his 10-year-old daughter to use three drug-sniffing dogs and an ounce of cocaine for a science fair project.

Douglas Bartelt, a detective with the Miami-Dade Police Narcotics Bureau, provided his daughter, Emma, with three detector canines and 28 grams of cocaine (street value: approximately $1,300) for her entry into Coral Gables Preparatory Academy's annual science fair.

Not surprisingly, she won.

?The purpose for this scientific investigation was to find which dog would find the cocaine fastest using it?s [sic] sense of smell,? the fourth grader wrote in the abstract for her project, entitled "Drug Sniffing Dogs."

According to the Miami Herald, Bartelt, fellow detective William Pedraja and Sgt. Samantha Machado provided the dogs (a springer spaniel named Roger; Levi, a golden retriever; and Franky, a retired chocolate labrador) and the cocaine. (Franky showed he's still got the touch, locating the illegal substance in 43 seconds.)

Emma's mother, Michelle Bartelt, said the experiment was her daughter's idea, and that Emma was under constant supervision and "did not touch the cocaine."

?[Doug] handled the drugs,? she said. ?He?s always very meticulous about how he handles drugs.?

John Schuster, a spokesman for the school district, issued a statement saying the project, while unusual, did not violate any of the science fair's rules--and that cocaine is not a specifically banned substance.

?The student?s science project involved a very unusual set of circumstances, including having a parent who is a well-respected police detective with experience in training dogs that sniff for illegal substances," Schuster's statement read. "From our understanding, the parent was the only person involved in working directly with the dogs and the hidden substances, which took place at a police training facility.?

The first-place honor gave Emma an automatic entry into the Miami-Dade Elementary Schools Science Fair, where her drug-sniffing project earned an honorable mention.

Source: http://news.yahoo.com/blogs/sideshow/science-fair-cocaine-drug-sniffing-dog-141435818.html

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Sony boosts Music Unlimited sound quality to 320kbps on Android, coming soon to...

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Source: http://www.facebook.com/MobileSyrup/posts/325730244194383

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Wednesday, January 30, 2013

Six weeks of free PlayStation Mobile gaming ? update 3 ...

PlayStation Mobile

Hi everyone. This week?s PlayStation Mobile giveaway title is Cubixx. Use your laser to cut away the surfaces of a mysterious cube and free the energy within. It?s a classic action puzzle game requiring split second decisions.

cubixx2cubixx1

Download it today from PS Store on PS Vita or PlayStation Certified Devices now, and we?ll see you back here next Wednesday for another complimentary PS Mobile game!

To find out more information about PlayStation Mobile, please visit http://eu.playstation.com/playstation-mobile/

Source: http://blog.eu.playstation.com/2013/01/30/six-weeks-of-free-playstation-mobile-gaming-update-3/

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Why Tackling Immigration Reform Won't Close the Rift Between the GOP and Hispanics

Leading Republicans are jumping on the immigration reform bandwagon, hoping that taking the issue off the table will give them a second chance to make inroads with Hispanic voters. But even with a bipartisan deal looking within reach, the Republican party may not benefit as much as strategists expect.

Indeed, there?s evidence that Hispanic resistance to the Republican party is as rooted in?the GOP?s skeptical view of government, as it is their disagreement with GOP hardliners on immigration. The Republican Party calls for smaller government, but many Latinos look to government assistance as a necessity. Forty-two percent of Hispanic voters say that a government job offers the best chance of gaining career success, compared to only one-third of white voters, according to a June?Allstate/National Journal/Heartland Monitor poll.

"Our argument about limited government is always harder to sell than a government program," Florida Sen. Marco Rubio told Rush Limbaugh on Tuesday. "It always has been. It's easier to sell cotton candy than it is to sell broccoli to someone, but the broccoli is better for you, and the same thing with a limited government."

That's the argument Republicans are banking on. Texas Sen. Ted Cruz made a similar pitch this weekend, saying that Hispanic voters should be a natural constituency for Republicans because 2.3 million of them own small businesses, and polls show that the economy, not immigration, is their top concern.

But attitudes about the government are not the only area where the GOP and Hispanics diverge. Asked whether they trusted President Obama and Democrats or Mitt Romney and Republicans on the economy, 71 percent of Latino voters preferred the president, according to a November?Latino Decisions poll. The president?polled?similarly well on a host of questions, including women's issues and foreign policy.?

Even on social issues where there is perceived to be a natural fit among religious Hispanic voters and the GOP, a divide exists. A majority of Hispanic voters now back gay marriage, according to a?Pew Research Center Poll, for instance.?

"I think Republicans are going to have to come up with a comprehensive plan for appealing to Hispanic voters," said one former GOP leadership aide. "Immigration is not going to solve the issue for them, but it will help."

So far that plan consists of talking about messaging. While Republicans acknowledge there's a communications gap with Hispanic voters, the strategy for repairing it remains murky. Many conservatives say it's time to retire language that could be viewed as nativist or racially insensitive. Adocument released Tuesday?by the Hispanic Leadership Network, a Republican outreach group, offers advice to conservatives in how to talk about immigration without using language that may inadvertently offend Hispanics.

"I think there are some in the movement who portray immigration as a potential threat to the fabric of the culture," said former-Democratic-Rep.-turned-Republican Artur Davis in an interview. "A Latino hears that. That doesn't sound the way you want it to sound and it raises all kinds of red flags."

Given the longstanding divide between Hispanics and the GOP on immigration, it?s hard to imagine all the damage will be resolved with one bipartisan reform bill. In California, Republicans did irreparable damage to their relationship with the state?s sizable Hispanic population after former GOP Gov. Pete Wilson backed Proposition 187 in 1994 that prohibited illegal immigrants from using government services.

"If the only time you talked to your wife was on an issue you disagreed about how good would your relationship be?" asked California Republican party chairman Tom Del Beccaro said. "Republicans need to talk to them about all the issues they care about."

Source: http://news.yahoo.com/why-tackling-immigration-reform-wont-close-rift-between-095013713--politics.html

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Michael B. Jordan Talks Taking Sundance By Storm In 'Fruitvale'

At this year's Sundance Film Festival, Dane DeHaan wasn't the only "Chronicle" alum to make a big impression with the critics in Park City, Utah. His co-star and former "Friday Night Lights" star Michael B. Jordan led his Sundance entry "Fruitvale" to wins in both the Grand Jury and Audience prizes at the festival. "Fruitvale" [...]

Source: http://moviesblog.mtv.com/2013/01/29/michael-b-jordan-fruitvale/

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Investing, Economics Mostly: Planning in Retirement

I have built a spreadsheet to talk about 5 year planning in retirement if you have a stock portfolio. When you take money from a stock portfolio, you want to ensure you have enough in cash and projected income to allow you to withdraw money in the next 5 years.

Basically in this scenario you expect to take out money from your RRSP stock fund, have pension income and to use the dividend income of your stock fund. If you are using money from a stock fund, you want to make sure you have enough for withdrawals over the next 5 years.

I am projecting a budget to increase by 3% per year, the pension income to increase by 2% per year and the dividend income to increase by 6% per year. (The dividend increase is quite conservative and 8% could also be used here.) See my first spreadsheet on my site at planning.htm.

Personally I use a similar sheet and change the month in column 1 each month and adjusted the budget and income left. So I track my progress month by month. See sample on my site at planning2.htm.

With the second spreadsheet, I have showed the information slightly differently and it shows that there is not enough money in either the Trading Account or the RRSP Account to cover withdrawals and therefore something would have to be sold to give the full 5 year coverage. For the Trading Account, you could also lower your budget. See my third spreadsheet on my site at planning3.htm.

In these spreadsheets, if you have a self-directed RRIF, you can just put the RRIF in the RESP spot. If you want a table showing the RRIF withdrawal rates, see Tax Tips site or the RRIF document from Canada Revenue Agency.

I use Quicken and I find it great for keeping track of my current investments. However, there is nothing like a spreadsheet to answer the question of "What if". There is why I use spreadsheet to project what I could likely expect in the next 5 years. However, with all projections, you are making assumptions. For example, I made an assumption of inflation at 3% in connection with my budget.

If you want a copy of the spreadsheet, just email me at brunner@rogers.com.

This blog is meant for educational purposes only, and is not to provide investment advice. Before making any investment decision, you should always do your own research or consult an investment professional. See my site for an index to these blog entries and for stocks followed. Follow me on Twitter.

Source: http://spbrunner3.blogspot.com/2013/01/planning-in-retirement.html

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Tuesday, January 29, 2013

Applegate wins Newbery; Klassen takes Caldecott

NEW YORK (AP) ? Katherine Applegate's "The One and Only Ivan" won the John Newbery Medal for the outstanding book of 2012, while Jon Klassen's "This Is Not My Hat" received the Randolph Caldecott Medal for outstanding illustration, the American Library Association announced Monday.

The Newbery and Caldecott awards are the top honors for children's literature.

Applegate's book tells of a daydreaming gorilla and the life lessons he receives through his friendship with a baby elephant. It was inspired by a real gorilla, one who lived decades without meeting another of his kind before spending his final, happy years at an Atlanta zoo.

Klassen was the author and illustrator of "This Is Not My Hat," his picture story about a fish and his blue hat, and the successor to Klassen's popular "I Want My Hat Back."

Bryan Collier's illustration for a book edition of Langston Hughes' poem "I, Too, Am America" received a Coretta Scott King prize for outstanding work by an African-American. Andrea Davis Pinkney's "Hand in Hand" won the King award for best text.

Alire Saenz's "Aristotle and Dante Discover the Secrets of the Universe" won twice: the Stonewall Book Award, for works about the gay, lesbian, bisexual or transgender experience, and the Pura Belpre Award for best Latino/Latina author. David Diaz's work on "Martin de Porres: The Rose in the Desert" won the Belpre for illustration.

Katherine Paterson, 80 years old and winner of the Newbery, the National Book Award and many other honors, received the Laura Ingalls Wilder prize for lifetime achievement.

Steve Sheinkin's "Bomb: The Race to Build ? and Steal ? the World's Most Dangerous Weapon" was named the best nonfiction book and the "most distinguished informational" book.

Source: http://news.yahoo.com/applegate-wins-newbery-klassen-takes-caldecott-172235200.html

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The Hobson and Holtz Report ? Podcast #688: January 28, 2013

FIRIntro: Welcome new listeners via the CIPR and MyNewsDesk, FIR Interview with PRCA?s Francis Ingham published, upcoming FIR Interview with Allan Schoenberg of CME Group, today is Data Privacy/Protection Day;

Quick News: Many ways brands can use Vine and a caveat, social media branding is key for company reputation, the Pope urges Catholics to flock to Twitter, Pew says libraries and print still have a place in an ebook world; Ragan promo;

News That Fits: Discussion on the 2013 Edelman Trust Barometer; Michael Netzley reports from Singapore on the latest internet statistics from China from WeAreSocial?s research; the Media Monitoring Minute with CustomScoop; listener comments; Boeing keeps key buyer informed during Dreamliner crisis; Dan York? reports on Data Privacy Day, and more; if you don?t participate in online social networks, will you become disenfranchised?;

Music from Steph Barrak; and more.

Listen Now:

Get FIR:

Messages from our sponsors: FIR is brought to you with Lawrence Ragan Communications, serving communicators worldwide for 35 years, www.ragan.com; Save time with the CustomScoop online clipping service: sign up for your free two-week trial, at www.customscoop.com/fir.

For Immediate Release: The Hobson & Holtz Report for January 28, 2013: A 79-minute podcast recorded live from Wokingham, Berkshire, England, and Concord, California, USA.


Links to websites, blog posts and other content we discuss in the show are posted as Delicious bookmarks to facilitate your connection with the discussions and sharing of that content.

FIR online communities

Share your comments or questions about this show, or suggestions for future shows, in the online FIR communities on Facebook, Friendfeed and Google+.

You can also email us at fircomments@gmail.com; call the Comment Line at +1 415 895 2971 (North America), +44 20 3239 9082 (Europe), or Skype: fircomments; comment at Twitter: @FIRpodcast. You can email your comments, questions and suggestions as MP3 file attachments, if you wish (max. 3 minutes / 5Mb attachment, please!). We?ll be happy to see how we can include your audio contribution in a show.

To stay informed about occasional FIR events (eg, FIR Live), sign up for FIR Update email news.

So, until Monday February 4?

(Cross-posted from For Immediate Release, Shel?s and my podcast blog.)

Source: http://www.nevillehobson.com/2013/01/28/the-hobson-and-holtz-report-podcast-688-january-28-2013/

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Russia says Assad's prospects fading

MOSCOW (Reuters) - Russia said the chances of Syrian President Bashar al-Assad staying in power were growing "smaller and smaller", as fighting on Sunday in southwestern Damascus shut a main highway from the capital.

Assad has long counted Moscow as an ally and Prime Minister Dmitry Medvedev's remarks were the most vocal Russian statement yet that his days may now be numbered, although they come after predictions from France, an avowed enemy, and from neighboring Jordan that the Syrian president's downfall is not imminent.

"I think that with every day, every week and every month, the chances of his preservation are getting smaller and smaller," Medvedev said, according to the transcript of an interview in Russian with CNN that was released by his office.

"But I repeat again, this must be decided by the Syrian people. Not Russia, not the United States, nor any other country," said Medvedev, whose administration has criticized Western, Turkish and Gulf Arab support for Syria's rebels.

"The task for the United States, the Europeans and regional powers ... is to sit the parties down for negotiations, and not just demand that Assad go and then be executed like Gaddafi or be carried to court sessions on a stretcher like Hosni Mubarak."

After Egypt's veteran president Hosni Mubarak was toppled, Russia withheld its veto on a U.N. Security Council resolution authorizing Western and Arab powers to provide military help to the rebels who overthrew Muammar Gaddafi in neighboring Libya.

Moscow has since accused the West of breaching sovereign rights and has vetoed U.N. action against Assad. Medvedev warned that removing Assad by force would mean "decades" of civil war.

Russia has been Assad's most important ally throughout the 22-month-old Syrian conflict, which began with peaceful street protests and evolved into an armed uprising against his rule.

Moscow has blocked three Security Council resolutions aimed at pushing him out or pressuring him to end the bloodshed which has killed more than 60,000 people. But Russia has also distanced itself from Assad by saying it is not trying to prop him up and will not offer him asylum.

The mainly Sunni Muslim rebels have seized territory in the north of the country, including several border crossings, and have challenged Assad's control over Syria's main cities.

But Assad's air power and army, whose senior ranks are dominated by his Alawite minority, have stemmed rebel advances.

France said on Thursday there was no sign Assad was about to be overthrown, reversing previous statements that he could not hold out long, and Jordan's King Abdullah said Assad would consolidate his grip for now.

"Anybody who is saying the regime of Bashar has got weeks to live really doesn't know the reality on the ground," Abdullah said in Davos on Friday. "They still have capability, so I give them a strong shot at least for the first half of 2013."

HIGHWAY CLOSED

Activists said rebels clashed with forces loyal to Assad in southwestern Damascus on Sunday, seizing a railway station and forcing the closure of the main highway to Deraa in the south.

Footage posted on the Internet showed what activists said was a rebel attack on the station in Qadam district. One clip showed gunmen taking cover as gunfire could be heard. Another showed gunmen inspecting buildings by the track after what the narrator describes as the "liberation" of the station.

Another video showed black smoke billowing above concrete buildings, the result of what activists said was an air strike by Assad's air force near the railway terminal.

Syrian media did not comment on the fighting around Qadam and restrictions on independent media make it difficult to verify reports from activists.

The Syrian Observatory for Human Rights, a British-based opposition group which monitors the violence in Syria, said jets and artillery also struck targets in rebel strongholds to the east and south of the capital after fierce clashes there.

The fighting came as United Nations humanitarian chief Valerie Amos visited Syria ahead of a U.N. aid conference in Kuwait which aims to raise $1.5 billion for millions of people made homeless, hungry and vulnerable by the conflict.

On Wednesday, Amos said Syrians were "paying a terrible price" for the failure of world powers to resolve the conflict, pointing to 650,000 refugees who have fled the country and the millions affected inside Syria.

"Four million people need help, two million are internally displaced and 400,000 out of 500,000 Palestinian refugees have been affected," she told an economic forum in Switzerland.

The United Nations and aid groups inside Syria, including the Syrian Arab Red Crescent, could not keep pace with the rising number of people in need, she said.

"We must find ways to reach more people, especially in the areas we are still unable to get to, and where there is ongoing fighting," she said.

Last month, the United Nations withdrew 25 of its 100 foreign aid workers from Syria as fighting intensified around Damascus, but Amos said it remained committed to maintaining aid work.

Most of the money from the Kuwait conference will go to support neighboring countries hosting hundreds of thousands of refugees, while $519 million is earmarked for aid inside Syria.

ISRAEL WARNING

The fighting has alarmed neighboring Israel, where Vice Prime Minister Silvan Shalom said that any sign that Syria's grip on its chemical weapons was slipping could trigger Israeli military strikes.

Should Lebanon's Hezbollah guerrillas or Syrian rebels obtain Syria's chemical weapons, "it would dramatically change the capabilities of those organizations," Shalom said.

Such a development would be "a crossing of all red lines that would require a different approach, including even preventive operations," he told Israel's Army Radio.

Assad has vowed to defeat rebels he describes as terrorists. In a speech three weeks ago he repeated his readiness for a national dialogue, but ruled out talking to "extremists who don't believe in any language but killing and terrorism".

State television said on Sunday that Syria's highest judicial council had suspended legal cases against Syrian opposition members so they can take part in talks - a proposal roundly rejected by most of Assad's opponents.

Medvedev said Assad did not appear to be ready for a negotiated solution to the crisis.

"He should have done everything much faster, attracting part of the moderate opposition, which was ready to sit at the table with him, to his side," the Russian premier said. "This was his significant mistake, and possibly a fatal one."

But he also warned of consequences if Assad is thrown out by force. He said: "Then the civil war will last for decades."

(Additional reporting by Dominic Evans in Beirut, Alistair Lyon in Amman, Dan Williams in Jerusalem; Writing by Dominic Evans; Editing by Alastair Macdonald)

Source: http://news.yahoo.com/russia-says-assads-prospects-fading-165439983.html

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Immigration Reform Proposals to be Submitted This Week - TalkLeft ...

A blueprint for immigration reform, including a path to citizenship some undocumented residents, is expected to be released this week by a 6 member Senate working group, that includes Senators Dick Durbin, John McCain, Lindsay Graham, Mark Rubio, Charles Schumer and Robert Menendez.

The Republicans in the group are going to stress tougher border security and more employer penalties. The Democrats (hopefully) will stress family reunification.

Mr. Durbin added that the effort will be focused on unifying families, and will include a version of the Dream Act, which would give undocumented students a path to permanent residency status.

[More...]

This month, Homeland Security Secretary Janet Napolitano announced a new rule published in the Federal Register, allowing for "provisional unlawful presence waivers":

Secretary of Homeland Security Janet Napolitano today announced the posting of a final rule in the Federal Register that reduces the time U.S. citizens are separated from their immediate relatives (spouse, children and parents), who are in the process of obtaining visas to become lawful permanent residents of the United States under certain circumstances.

The final rule establishes a process that allows certain individuals to apply for a provisional unlawful presence waiver before they depart the United States to attend immigrant visa interviews in their countries of origin. The process will be effective on March 4, 2013 ....?This final rule facilitates the legal immigration process and reduces the amount of time that U.S. citizens are separated from their immediate relatives who are in the process of obtaining an immigrant visa,? said Secretary Napolitano.

President Obama will address the issue in Las Vegas on Tuesday:

Obama is to press his case for immigration changes during a trip to Las Vegas Tuesday: a pathway to citizenship for illegal undocumented immigrants that includes paying fines and back taxes; increased border security; mandatory penalties for businesses that employ unauthorized immigrants; and improvements to the legal immigration system, including giving green cards to high-skilled workers and lifting caps on legal immigration for the immediate family members of U.S. citizens.

For more on the family issues, see UniteFamilies.org

Source: http://www.talkleft.com/story/2013/1/27/164520/223

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Monday, January 28, 2013

Russian court postpones hearing in whistleblower's case

MOSCOW (Reuters) - A Moscow court postponed a preliminary hearing on Monday in the posthumous trial of whistleblower Sergei Magnitsky, whose death in custody has damaged Russia's image and strained ties with the United States.

The court appointed a legal team to defend Magnitsky during the trial after his family and lawyers refused to attend Monday's hearing because they say the case is politically motivated.

Magnitsky was 37 when he died after 358 days in jail on suspicion of tax evasion and fraud, during which he said he was denied treatment as his health declined.

"Today's preliminary court hearing was moved to February 18 ... because Magnitsky's defence team did not show up. And the judge, in order to observe the principle of equality (before the law), appointed a defense," said court spokeswoman Alexandra Berezina.

Russian authorities said Magnitsky died of a heart attack. But his former employer, investment fund Hermitage Capital, says he was killed because he was investigating a $230 million theft by law enforcement and tax officials.

(Reporting by Thomas Grove, Editing by Timothy Heiortage)

Source: http://news.yahoo.com/russian-court-postpones-hearing-whistleblowers-case-091503115.html

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2013 Farmers Insurance Open: Tee times and TV schedule for ...

The third round of the 2013 Farmer Insurance Open will resume Sunday, with most golfers having yet to tee off thanks to a fog delay on Saturday. Check out where and when to tune in to see Tiger Woods attempt to hold off the pack at Torrey Pines.

Play will resume at 7:00 a.m. at Torrey Pines (10:00 a.m. ET) after fog delayed the third round of the 2013 Farmers Insurance Open on Saturday. A grand total of one hole was played Saturday, and leader Tiger Woods has yet to begin his third round in the lead grouping. He entered the day at 11-under overall, two strokes ahead of Billy Horschel in second place.

For more, visit SB Nation's Golf hub

You can catch lead-in coverage on the Golf Channel from 1:00-2:30 p.m. ET, and live coverage from 3:00-6:30 p.m. ET on CBS. The Golf Channel will have replay coverage from 7:00 p.m. into the late night. You can also tune into PGA Tour Network on Sirius XM Radio from 1:00-7:00 p.m. for more.

Sunday's schedule will look a lot like Saturday's as a result of the fog, with the final round to be played Monday. You can check out the top groupings below. For a full list of tee times, check out PGATour.com. You can also visit Golf.com for a full leaderboard.

Note: All times Eastern.

  • 11:40 a.m.: Phil Mickelson, Aaron Baddeley, Martin Laird (Tee No. 10)
  • 11:40 a.m.: Luke Guthrie, John Senden, Tag Ridings (Tee No. 1)
  • 11:50 a.m.: Matt Every, Eric Meierdierks, James Hahn (Tee No. 10)
  • 11:50 a.m.: Jimmy Walker, Josh Teater, Nick Watney (Tee No. 1)
  • 12:00 a.m.: Scott Gardiner, Steve LeBrun, Doug LaBelle II (Tee No. 10)
  • 12:00 a.m.: Brad Fritsch, Erik Compton, Steve Marino (Tee No. 1)
  • 12:10 a.m.: Tiger Woods, Billy Horschel, Casey Wittenberg (Tee No. 1)
  • ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

    Source: http://www.sbnation.com/golf/2013/1/27/3920842/farmers-insurance-open-golf-2013-tv-schedule-tee-times-sunday

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    Time to retire chimps in US research labs?

    Scientists have a proposal to retire all but 50 research chimpanzees kept in US federal labs. The primates would be sent to 'Chimp Haven,' a new chimp sanctuary in Louisiana. Animal rights activists applaud the move.

    By Janet McConnaughey,?Associated Press / January 23, 2013

    A 200-acre site near Shreveport, La., in 2004 when the first phase of construction on Chimp Haven was underway. The NIH Council of Councils Working Group on Tuesday Jan. 22, 2013 approved a proposal, which also calls for major cuts in grants to study chimps in laboratories and no return to breeding them for research.

    (AP Photo/Chimp Haven, Naomi Lopez-Bauman)

    Enlarge

    Government scientists have agreed that all but 50 of hundreds of chimpanzees kept for federally funded research should be retired from labs and sent to a national sanctuary.

    Skip to next paragraph

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    The proposal from a National Institutes of Health committee also said all of the chimps should have plenty of room to play and climb.

    The NIH Council of Councils Working Group on Tuesday approved the proposal, which also calls for major cuts in grants to study chimps in laboratories and no return to breeding them for research.

    Already, nine chimpanzees arrived Tuesday at Chimp Haven outside Shreveport, La., from the University of Louisiana at Lafayette's New Iberia Research Center, which no longer has an NIH chimp research contract. Seven more are expected Thursday and another 95 will arrive over the coming months, sanctuary officials said.

    The federal agency said in 2011 that it would phase out most invasive research on chimpanzees. The new 86-page recommendation describes how chimpanzees should be kept and what will be needed for any future research. Chimps should be used only if there is no other way to study a threat to human health, and the research should be approved by an independent committee with members from the public, said the Council of Councils proposal, which will be sent to the NIH's director after a 60-day public-comment period.

    Animal-rights activists said they were pleased by the recommendations.

    "At last, our federal government understands: A chimpanzee should no more live in a laboratory than a human should live in a phone booth," the People for the Ethical Treatment of Animals said in a statement.

    Chimp Haven was created on 200 acres of a Caddo Parish park in Keithville in northwest Louisiana.

    "We should see more than 300 chimpanzees getting moved to the federal sanctuary system," said Kathleen Conlee, the Humane Society of the United States' vice president for animal research issues.

    But Conlee said she was disappointed by the recommendation to keep a group of about 50 in case further research on chimpanzees is approved.

    "But I'm glad they made clear those animals should be kept to much higher standards than they are currently being kept in," she said.

    Chimpanzees should be kept in groups of at least seven, with about 1,000 square feet of outdoor space per chimp ? roughly one-sixth of an acre for a group of seven, according to the proposal.

    The space must include year-round outdoor access with a variety of natural surfaces such as grass, dirt and mulch, and enough climbing space to let all members of large troupes travel, feed and rest well above the ground, and with material to let them build new nests each day, the report said.

    Chimp Haven's enclosures range from a quarter-acre to five acres, some of them forested and all with climbing structures.

    The announcement of its first animals from the University of Louisiana at Lafayette's New Iberia Research Center was delayed a day to keep stress on them to a minimum, officials said.

    "Understandably, the chimpanzees are nervous when they arrive, and we do everything possible to ease their stress. That includes limiting the number of people in the area to only those who are required to help with the chimpanzees. We also must minimize the risks of the chimpanzees being exposed to communicable diseases," veterinarian Raven Jackson said in the news release.

    A $30 million cap on total spending for construction and care of Chimp Haven's retirees has been looming. That would stop NIH from contributing 75 percent of the $13,000 annual cost to care for each federal chimpanzee.

    Conlee said the Humane Society will urge Congress to move money now spent on research contracts to Chimp Haven. The sanctuary gives the animals better care for less money than the labs are paid, she said.

    Copyright 2013 The Associated Press.

    Source: http://rss.csmonitor.com/~r/feeds/science/~3/yg7p6VWLHHc/Time-to-retire-chimps-in-US-research-labs

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    Saturday, January 26, 2013

    Austerity? Britain's economy shrinks toward 'triple dip'

    LONDON (Reuters) - Britain's economy shrank more than expected at the end of 2012 with a North Sea oil production slump, lower factory output and a hangover from London Olympics pushing it perilously close to a "triple-dip" recession.

    The country's gross domestic product fell 0.3 percent in the fourth quarter, the Office for National Statistics said on Friday, a sharper fall than the 0.1 percent decline forecast by analysts.

    The news is a blow for Britain's Conservative-led government, which a day earlier defended its austerity program against criticism from the International Monetary Fund. It needs solid growth to meet its budget targets, keep a triple-A debt rating and bolster its chances of winning a 2015 election.

    Sterling fell to its lowest in 13-1/2 months against the euro and hit a five-month low against the dollar in response to the data. The euro was also buoyed by a stronger-than-expected German Ifo sentiment survey.

    "This is a very disappointing outturn," said Philip Shaw, economist at Investec in London. "Clearly now the talk will focus on whether we are in a triple dip recession. Certainly the news is unwanted."

    Britain's economy is now 3.3 percent smaller than its peak in Q1 2008, having recovered only about half the output lost during the financial crisis - a worse performance than most other major economies.

    The country slipped back into recession in the last three months of 2011, and only emerged from it in the third quarter of 2012, after a boost from the London Olympics.

    After a bout of inclement snowy weather in January - which is likely to have hit spending and output - the risk is that the economy will continue to shrink in the first three months of this year, technically pushing it into a rare and unwelcome "triple dip" recession.

    Britain's biggest department store group, John Lewis , said earlier on Friday that snow was responsible for its sales growth stalling in the latest week.

    POLITICALLY INCENDIARY

    In economic terms, the picture remains one of stagnation over the past year. But politically, the latest dip in national output is more incendiary.

    "Stagnation is going to be the theme for the next couple of quarters or so. This obviously brings Osborne's strategy into sharp relief and also the (Bank of England) strategy of maintaining or not sanctioning further monetary policy action," said Rob Wood at Berenberg Bank. "The Bank of England were forecasting a return to some growth in Q1 and that is likely to be disappointed."

    Finance minister George Osborne stuck fast to his austerity plan on Thursday, rejecting suggestions from the International Monetary Fund's chief economist that he should consider slowing his deficit reduction plan.

    Prime Minister David Cameron this week staked his political future on offering a referendum on Britain's place in the European Union. But it is Osborne's gamble that austerity will deliver strong growth before a 2015 election that will be crucial in determining his Conservative party's chance of winning.

    After the figures were released, the Treasury conceded that Britain still faced a "very difficult economic situation".

    "While the economy is healing, it is still a difficult road," it said in a statement.

    Britain's chief central banker Mervyn King expects no more than a "gentle recovery" this year, while this week the IMF cut its 2013 forecast for British economic growth to 1.0 percent from 1.1 percent predicted in October.

    However, economists and business groups warn that even such lackluster growth could be derailed by a hit to firms' and consumers' confidence from talk of a triple-dip recession.

    That prospect will add to pressure on the ruling coalition of Conservatives and Liberal Democrats to loosen its deficit-cutting drive and bolster the economy as George Osborne prepares his 2013 budget, due in March.

    The biggest driver for the fourth-quarter fall in GDP was a 10.2 percent drop in mining and quarrying output, the biggest since records began in 1997, driven by disruption from extended maintenance affecting North Sea oil and gas fields.

    This knocked 0.18 percent off GDP, while slightly smaller amounts of damage were done by falls in factory output and in the 'government and other services' category, where the Olympics had boosted sports and recreation services in the third quarter.

    Friday's figures showed output in the service sector -- which makes up more than three quarters of GDP -- was flat in the fourth quarter. Industrial output was 1.8 percent lower.

    (Reporting by David Milliken and Olesya Dmitracova, writing by Mike Peacock. Editing by Jeremy Gaunt.)

    Source: http://news.yahoo.com/uk-gdp-falls-more-forecast-fourth-quarter-094734833--business.html

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    New target for rheumatoid arthritis drugs

    Jan. 25, 2013 ? Researchers at Hospital for Special Surgery have identified a potential new target for drugs to treat patients with rheumatoid arthritis (RA), a protein known as IRHOM2. The finding could provide an effective and potentially less toxic alternative therapy to tumor necrosis factor-alpha blockers (TNF-blockers), the mainstay of treatment for rheumatoid arthritis, and could help patients who do not respond to this treatment. Efforts to develop drugs that hone in on this new target are underway.

    "This study is an elegant example of the capacity of basic science cell biologists to work with translational rheumatologists to address a clinically relevant question at a basic level," said Jane Salmon, M.D., Collette Kean Research Chair and co-director, Mary Kirkland Center for Lupus Research at Hospital for Special Surgery (HSS) in New York City, and an author of the study. "We have identified a clinically relevant target that can be applied to patients in the near term." The study will appear online, ahead of print, on January 25, in the Journal of Clinical Investigation and in the February 2013 print issue.

    Rheumatoid arthritis, an autoimmune disease, is triggered, in large part, by TNF-alpha, a small signaling protein usually involved in launching protective systemic inflammatory responses. With excessive TNF production, however, immune cells can become activated inappropriately and cause tissue inflammation. This produces a number of diseases, including RA. While TNF-blockers help many RA patients, these treatments are very expensive, and some patients do not respond. For this reason, researchers have been searching for alternative targets in patients with inflammatory diseases against which drugs can be directed.

    "TNF can be thought of as a balloon tethered to the surface of cells. To work, it must be cut loose by signaling scissors called TACE (TNF-alpha converting enzyme)," said Carl Blobel, M.D., Ph.D., program director of the Arthritis and Tissue Degeneration Program at HSS. While blocking TACE could be another way to treat rheumatoid arthritis, researchers know this strategy would likely have side effects since patients lacking TACE are prone to skin infections and intestinal lesions.

    Earlier this year, HSS investigators demonstrated that the TACE scissors are regulated by molecules called IRHOM1 and IRHOM2, which are thought to wrap around TACE and help it mature into functional scissors. They also demonstrated that mice that are genetically engineered to lack IRHOM2 lack functional TACE on the surface of their immune cells and don't release TNF. Surprisingly, these mice are healthy, and do not develop skin or intestinal defects.

    In the current study, HSS researchers set out to investigate why this paradox exists. After examining tissues of IRHOM2-deficient mice, they found that IRHOM2 regulates TACE on immune cells, whereas IRHOM1 is responsible for helping TACE mature elsewhere in the body, such as in brain, heart, kidney, liver, lung and spleen cells. "IRHOM2 appears to have a more restrictive and exclusive function in immune cells," said Dr. Blobel.

    The researchers then set out to determine whether blocking IRHOM2 could be a strategy to treat RA. They used a mouse model that mimics human rheumatoid arthritis in mice genetically engineered to be deficient in IRHOM2. They found that these rodents did not develop inflammatory arthritis and were otherwise healthy.

    "When we tested mice that don't have IRHOM2 in a model for inflammatory arthritis, we found they were protected and they were protected as well as mice that didn't have any TNF," said Dr. Blobel. "Because TNF is the driver of rheumatoid arthritis in human disease, as evidenced by how well anti-TNF drugs work, we feel that this provides a completely new angle on blocking TNF release. It would be wonderful to be able to inactivate TACE in a tissue-specific manner and IRHOM2 provides a unique mechanism for us to do so."

    Using drugs that inactivate IRHOM2 in humans, clinicians will be able to block the function of TACE only in immune cells. "We can prevent the deleterious contribution of TACE to rheumatoid arthritis patients and preserve its protective function in skin and intestines," said Dr. Blobel. "With IRHOM2, we have a unique and unprecedented opportunity to inactive TACE only in certain cell types, and not in others, and there is currently no other effective way of doing that."

    The researchers say the next step is to identify antibodies or pharmacological compounds that can be used to block the function of IRHOM2 and are safe in patients. These HSS investigators are currently working to identify and test such agents. "In theory, IRHOM2-targeted drugs will have less toxicity than TNF alpha blockers," said Dr. Salmon. "They block TNF release only from specific cells, those known to contribute to joint inflammation and damage."

    Dr. Salmon and Dr. Blobel are co-senior authors of the study. Other investigators involved in the study are from Weill Cornell Medical College, New York City; Ontario Cancer Institute, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada; Heinrich-Heine University, Dusseldorf, Germany; TriInstitutional Laboratory of Comparative Pathology, New York City; and Keio University, Tokyo, Japan.

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    Story Source:

    The above story is reprinted from materials provided by Hospital for Special Surgery.

    Note: Materials may be edited for content and length. For further information, please contact the source cited above.


    Journal Reference:

    1. Priya Darshinee A. Issuree, Thorsten Maretzky, David R. McIlwain, S?bastien Monette, Xiaoping Qing, Philipp A. Lang, Steven L. Swendeman, Kyung-Hyun Park-Min, Nikolaus Binder, George D. Kalliolias, Anna Yarilina, Keisuke Horiuchi, Lionel B. Ivashkiv, Tak W. Mak, Jane E. Salmon, Carl P. Blobel. iRHOM2 is a critical pathogenic mediator of inflammatory arthritis. Journal of Clinical Investigation, 2013; DOI: 10.1172/JCI66168

    Note: If no author is given, the source is cited instead.

    Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

    Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/oyUne2dxrpw/130125142044.htm

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    Friday, January 25, 2013

    NuForce HP-800


    Studio monitor headphones are an interesting, refreshing breed. In this age of mega-boosted bass, the goal of a studio monitor pair, like the NuForce HP-800, is to reproduce sound accurately, not overwhelmingly. Thus, the $149 (list) HP-800 does not throttle your ears with sub-bass frequencies. Instead, it focuses on the mid-range content, producing an accurate, crisp sound signature that is ideal for many genres. Unfortunately, any genre that relies on deep, sub-bass content as a central part of its mix is bound to give the HP-800 some trouble. These headphones not only seem to lack much sub-bass presence at moderate levels, but they distort on these same frequencies at top volumes.?

    Design
    The circumaural (over-the-ears) design of the visually-striking HP-800 is basically a must for studio monitors pairs?on-ear pairs tend to bleed too much audio that could then be picked up by microphones. NuForce uses memory foam in the ear pads, adding a layer of comfort that is crucial for long recording sessions.

    Two nice visual touches on the otherwise uniformly black frame: The drivers on the inside of the earcups are covered with bright red speaker grille cloth, and the square, gold-colored logo (which simply says "Nu") on the outside panels of the ears looks luxurious, not tacky. An innovative headband design actually uses two bands. The one that rests on your head is flexible and adjusts automatically based on tension, while the top band is more rigid and helps stabilize the fit.NuForce HP-800 inline

    The detachable cable adds some value to the cost of the HP-800?cables are usually the most likely suspect when headphones malfunction. Being able to replace them, rather than send the unit in for a repair or buy a new pair altogether, could quite possibly extend the life of your headphones by years.

    Of the two included cables, one has a thick, cloth-covered outer layer, and terminates in either 3.5mm, or ?-inch for pro-gear jacks (a screw-on adapter is included). The other is quite thin, and is intended for on-the-go, non-studio use. It would've been nice to see phone controls included on this cable, but NuForce skipped phone controls, microphones, and remotes altogether, so this is a purely musical headphone pair. A black satin drawstring bag is also included.

    Performance
    NuForce more or less nails the flat frequency response most studio monitors need to have to be taken seriously. But the HP-800 lacks one crucial quality for a reliable pair of studio headphones: It can't handle deep bass at high volumes without distorting. This is really a shame, because its crisp, articulate response is ideal for studio engineers seeking an accurate portrayal of their project. If the track has serious sub-bass, like The Knife's "Silent Shout," or highly resonant low-end, like Thom Yorke's "Cymbal Rush," you're going to hear some very noticeable distortion at higher volumes.

    In a studio setting, this is especially an issue because you're typically listening to unmixed, un-mastered audio as you record, and deep bass is a part of many modern genres. Before it's been tamed by an engineer, it's often going to be loud in a mix. Unfortunately, one common aspect of studio monitoring, at least by musicians, is that the volume levels go up as the day gets longer, so this distortion is bound to rear its ugly head at some point.

    However, at moderate levels, the HP-800 does not distort on those deep bass tracks. Its overall bass response is quite subtle?typical for a studio monitor, but if it wasn't already obvious, this is not a pair for deep bass lovers. What the HP-800 focuses on is the midrange, and the highs, offering just enough sub-bass response to fill out the range. In this sense, it is unique in today's landscape of bass-boosted headphones, like the Beats by Dr. Dre.

    The focus on mids is ideal for engineers, but also sounds great on vocal-driven music. Bill Callahan's "Drover" can sound murky on some bass-heavy headphones, but on the HP-800, the treble edge on his unique baritone vocals is sharp, pushing it to the front of the mix where it belongs. Meanwhile, the thunderous drum sounds that underpin much of the verse are not overly bass-boosted, and sound natural and powerful?and not like they're the focus of the song, as they can sound if the lower bass frequencies are too intense.

    On classical tracks, like John Adams' "The Chairman Dances," the lower register strings have an almost perfect level of resonance and depth to them. Because the strings' sound signature doesn't exist too much in the sub-bass category, the HP-800 is able to reproduce them with a nice sense of body; they sound anything but anemic. The higher register strings, brass, and woodblock percussion sounds crisp, bright, and lively here, as you'd expect from a studio monitor pair. While the focus is definitely on the mids, the depth of the lower strings and larger percussion is still part of the mix. It's a very faithful, natural sound. Occasionally, things can sound a bit too focused on the hi-mids?some higher stringed instruments can sound a bit harsh at times, but this only really becomes an issue at top volumes.

    The limited sub-bass presence is felt mostly on modern pop, hip-hop, and rock mixes. On Jay-Z and Kanye West's "No Church in the Wild," the sub-bass synth hits lack gusto, and the kick-drum loop, which is already treble-heavy, but relies on nice low-end sustain to round it out, sounds a bit too crisp, and doesn't have much bass presence to it, either. The vocals come out clearly and nicely, and the occasional muddiness that can occur on a bass-heavy headphone with a dense mix like this one is never an issue. But the bass response here feels more implied than delivered, and for modern mixes, that eliminates much of a track's energy.

    If deep, booming bass is what you seek, the aforementioned Beats are an obvious place to start, but consider the more refined, yet still powerful, bass response of the Yamaha PRO 500. Hopefully, however, you're more interested in an accurate response, perhaps with more low frequency push than the HP-800 has, but nothing over the top. Sennheiser has mastered that sound signature, and although it leaks too much to be a good studio pair, the Sennheiser HD 558 is about as good as headphones can sound under $200.

    If you're looking for an even more affordable studio monitor pair, the Shure SRH440 offers a solid, accurate response, and doesn't suffer distortion issues. At $149, the NuForce HP-800 delivers an accurate sound, but its distortion issues on deep bass, and its limited bass response in general, make it a less-than-versatile studio tool. Basically, if you record music that has no sub-bass content, it's a great find, and if that's not the case, the HP-800 is not nearly as valuable to you.

    More Headphone Reviews:
    ??? NuForce HP-800
    ??? TDK EB950
    ??? Parrot Zik
    ??? Pioneer HDJ-2000
    ??? MartinLogan Mikros 70
    ?? more

    Source: http://feedproxy.google.com/~r/ziffdavis/pcmag/~3/fa7sWsPufBA/0,2817,2414484,00.asp

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    Movie Review: Gangster Squad

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    Having starred in 17 novels, Jack?Reacher is already quite well-known?to devoted fans of British author?Lee Child?s action antihero, but?millions more will be introduced to?the character via this upcoming Tom?Cruise vehicle. Jack Reacher, an?adaptation of the novel One Shot,?has Cruise playing the ex-military?police officer ...

    Movie Review: ?The Dark Knight Rises?

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    Spidey gets unleashed.The Amazing Spider-Man focuses on the?untold story of Peter Parker and his quest to find?the clues that he hopes will lead to his parents. The new film stars Andrew Garfield (The Social?Network) as the new Peter Parker and Emma?Stone (The Help) ...

    Movie Review: The Raid (?Serbuan Maut?)

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    Big spending China threatens J-League's reign

    By JOHN DUERDEN

    Associated Press

    Associated Press Sports

    updated 4:08 a.m. ET Jan. 25, 2013

    SINGAPORE (AP) -The Chinese Super League has shaken off corruption scandals and is spending big on international stars sparking debate as to how much ground it has made up on a Japanese J-League coping with a continuing exodus of young talent.

    A growing number of the J-League's best players are heading to European teams. 2012 Olympic star Kensuke Nagai left Nagoya Grampus earlier in January to join Standard Liege of Belgium, while Genki Omae became the 11th Japanese player to join Germany's top tier, shifting to Fortuna Dusseldorf from Shimizu S-Pulse.

    Shimizu coach Afshin Ghotbi told Associated Press he would like to see more done to ensure talent remains longer, or at least teams receive transfer fees of sufficient size to allow investment in developing talent.

    "J-League clubs have to do a better job in keeping players in Japan by signing longer term contracts and renewing them prior to their final year," said Ghotbi who added that the rise of Chinese football is good for Japan.

    "Due to the number and quality of the young Japanese players, the J-League has been able to sustain its quality, but unless measures are taken, at some point we will see a decline in the quality and popularity of the league."

    The booming Chinese league has overtaken the J-League in terms of average attendance, partly due to major investment in overseas talent.

    Guangzhou Evergrande, Guangzhou R&F, Shanghai Shenhua and Dalian Aerbin are also in the process of signing foreign players of higher quality than their Japanese counterparts.

    Speculation as to whether Didier Drogba and Nicolas Anelka will spend another season with Shanghai Shenhua has overshadowed some interesting purchases by Chinese clubs.

    Marcello Lippi, who led Italy to the 2006 World Cup, and now coach of Guangzhou Evergrande, splashed out $7.4 million in December on Brazil's Elkeson de Oliveira Cardoso to add to a squad that reached the last eight of the 2012 Asian Champions League.

    Guangzhou also won a second successive Chinese championship with a squad of Chinese national team players and highly-rated and highly-paid imports such as Dario Conca and Lucas Barrios.

    Dalian Aerbin signed French international Guillaume Hoarau from Paris Saint Germain. At 28, Hourau is no veteran approaching the end of his career, but a talented player at the peak of his career.

    U.S.-born Tom Byer played in Japan in the forerunner to the J-League and since retiring has played an influential role in the country's highly-rated youth development system. He is now Head Technical Consultant to the Chinese School Football Program administered by the Ministry of Education.

    "China is surely signing bigger marquee players than the J. League," Bayer said. "It seems like the `90s in Japan when every club had to have one or two stars. Time will tell if the Chinese Super League will get it right with the massive investment that some clubs are making."

    The departure of talent from Japan has its positives according to Byer, who believes that it has made the J-League more competitive. 2008 Asian Champion Gamba Osaka was relegated in 2012 while seven-time champion Kashima Antlers has fallen on lean times leaving relatively unfashionable teams such as Kashiwa Reysol, Vegalta Sendai and Sanfrecce Hiroshima to challenge for titles.

    Philippe Troussier, coach of the Japan national team from 1998 to 2002 who is now plying his trade in China, acknowledges that while the departure of talented players can weaken the J-League in the short-term, it will be of long-term benefit to Japan.

    "There are in Japan a high number of talented players for the future and the fact that some of them go to overseas can give to the local players more opportunities to play," the Frenchman said.

    When Shinji Kagawa, now of Manchester United, left Cerezo Osaka in 2010 to join Borussia Dortmund, Hiroshi Kiyotake cemented his place in the team's starting lineup. So impressive was the midfielder that he broke into the Japan national team and earned a move to FC Nuremberg in the Bundesliga.

    "We have many young players challenging overseas, especially in Europe. Even though many talented players move, we still have a lot of promising young players in the J-League and they grow through actual opportunities to play," the J-League's head of public relations, Kazayuki Hagiwara, said. "Players coming back share their unique experience. In the medium and long term, this virtuous cycle helps Japanese football develop."

    And far from being a threat to Japan, Hagiwara also claims that the rise of China is a positive.

    "Developing football in Asia, including China, and improving Asian football's position in the world is very important for the J-League."

    According to the well-traveled Troussier, China still has some way to go.

    "We can compare the current Chinese policies with Japanese policies 20 years ago," he said. "Chinese football looks very attractive at the moment with so many talented foreign players and coaches but it still needs a long time to reach a high football standard."

    ? 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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    Source: http://nbcsports.msnbc.com/id/50584408/ns/sports-soccer/

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    Don?t ignore the snore: Snoring may be early sign of future health risks

    Jan. 24, 2013 ? Here's a wake-up call for snorers: Snoring may put you at a greater risk than those who are overweight, smoke or have high cholesterol to have thickening or abnormalities in the carotid artery, according to researchers at Henry Ford Hospital in Detroit.

    The increased thickening in the lining of the two large blood vessels that supply the brain with oxygenated blood is a precursor to atherosclerosis, a hardening of the arteries responsible for many vascular diseases.

    "Snoring is more than a bedtime annoyance and it shouldn't be ignored. Patients need to seek treatment in the same way they would if they had sleep apnea, high blood pressure or other risk factors for cardiovascular disease," says lead study author Robert Deeb, M.D., with the Department of Otolaryngology-Head & Neck Surgery at Henry Ford.

    "Our study adds to the growing body of evidence suggesting that isolated snoring may not be as benign as first suspected. So instead of kicking your snoring bed partner out of the room or spending sleepless nights elbowing him or her, seek out medical treatment for the snorer."

    The study reveals changes in the carotid artery with snorers -- even for those without sleep apnea -- likely due to the trauma and subsequent inflammation caused by the vibrations of snoring.

    Study results will be presented January 25 at the 2013 Combined Sections Meeting of the Triological Society in Scottsdale, Ariz. It has been submitted to The Laryngoscope journal for publication.

    Obstructive sleep apnea (OSA) -- a sleep disorder that occurs due to the collapse of the airway in the throat during sleep and causes loud snoring and periodic pauses in breathing -- has long been linked to cardiovascular disease, along with a host of other serious health issues.

    But the risk for cardiovascular disease may actually begin with snoring, long before it becomes OSA. Until now, there was little evidence in humans to show a similar connection between snoring and cardiovascular risk.

    For the Henry Ford study, Dr. Deeb and senior study author Kathleen Yaremchuk, M.D., reviewed data for 913 patients who had been evaluated by the institution's sleep center.

    Patients, ages 18-50, who had participated in a diagnostic sleep study between December 2006 and January 2012 were included in the study. None of the participants had sleep apnea.

    In all, 54 patients completed the snore outcomes survey regarding their snoring habits, as well as underwent a carotid artery duplex ultrasound to measure the intima-media thickness of the carotid arteries.

    Carotid intima-media thickness, a measurement of the thickness of the innermost two layers of the arterial wall, may be used to detect the presence and to track the progression of atherosclerotic disease. Intima-media thickness is the first sign of carotid artery disease.

    Compared to non-snorers, snorers were found to have a significantly greater intima-media thickness of the carotid arteries, the study finds.

    The study also revealed no statistically significant differences in intima-media thickness for patients with or without some of the traditional risk factors for cardiovascular disease -- smoking, diabetes, hypertension or hypercholesterolemia.

    "Snoring is generally regarded as a cosmetic issue by health insurance, requiring significant out-of-pocket expenses by patients. We're hoping to change that thinking so patients can get the early treatment they need, before more serious health issues arise."

    The Henry Ford research team plans to conduct another long-term study on this topic, particularly to determine if there's an increased incidence of cardiovascular events in patients who snore.

    Along with Drs. Deeb and Yaremchuk, Henry Ford study co-authors are Paul Judge, M.D.; Ed Peterson, Ph.D.; and Judith C. Lin, M.D.

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    The above story is reprinted from materials provided by Henry Ford Health System.

    Note: Materials may be edited for content and length. For further information, please contact the source cited above.


    Note: If no author is given, the source is cited instead.

    Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

    Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/heart_disease/~3/yw8Pk1xU1ng/130124122741.htm

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    Thursday, January 24, 2013

    Controlled crumpling of graphene forms artificial muscle

    Jan. 23, 2013 ? Duke University engineers are layering atom-thick lattices of carbon with polymers to create unique materials with a broad range of applications, including artificial muscles.

    The lattice, known as graphene, is made of pure carbon and appears under magnification like chicken wire. Because of its unique optical, electrical and mechanical properties, graphene is used in electronics, energy storage, composite materials and biomedicine.

    However, graphene is extremely difficult to handle in that it easily "crumples," which, depending on circumstances, can be a positive or negative characteristic. Unfortunately, scientists have been unable to control the crumpling and unfolding of large-area graphene to take advantage of its properties.

    Duke engineer Xuanhe Zhao, assistant professor in Duke's Pratt School of Engineering, likens the challenge of controlling graphene to the difference between unfolding paper and wet tissue.

    "If you crumpled up normal paper, you can pretty easily flatten it out," Zhao said. "However, graphene is more like wet tissue paper. It is extremely thin and sticky and difficult to unfold once crumpled. We have developed a method to solve this problem and control the crumpling and unfolding of large-area graphene films."

    The Duke engineers attached the graphene on a rubber film that had been pre-stretched multiple times of its original size. Once the pre-stretch in the rubber film was relaxed, part of the graphene detached from the rubber while other part kept adhering on the rubber, forming an attached-detached pattern with a size of a few nanometers. As the rubber was relaxed, the detached graphene was compressed to crumple. Once the rubber film was stretched back, the adhered graphene will pull on the crumpled graphene to unfold it.

    "In this way, the crumpling and unfolding of large-area atomic-thick graphene can be controlled by simply stretching and relaxing a rubber film, even by hand," Zhao said.

    The results were published online in the journal Nature Materials.

    "Our approach has opened avenues to exploit unprecedented properties and functions of graphene," said Jianfeng Zang, a postdoctoral fellow in Zhao's group and the first author of the paper. "For example, we can tune the graphene from being transparent to opaque by crumpling it, and tune it back by unfolding it."

    In addition, the Duke engineers layered the graphene with different polymer films to make a "soft" material that can act like muscle tissues by contracting and expanding on demand. When electricity is applied to the graphene, the artificial muscle expands in area; when the electricity is cut off, it relaxes. Varying the voltage controls the degree of contraction and relaxation, giving actuation strains over 100 percent.

    "Indeed, the crumpling and unfolding of graphene allows large deformation of the artificial muscle." Zang said.

    "New artificial muscles are enabling diverse technologies ranging from robotics and drug delivery to energy harvesting and storage," Zhao said. "In particular, they promise to greatly improve the quality of life for millions of disabled people by providing affordable devices such as lightweight prostheses and full-page Braille displays. The broad impact of new artificial muscles is potentially analogous to the impact of piezoelectric materials on the global society."

    Zhao's work is supported by the National Science Foundation's (NSF) Triangle Materials Research Science and Engineering Center, NSF Materials and Surface Engineering program, and National Institutes of Health (NIH). Other members of the team are Duke's Qiming Wang and Qing Tu.

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    Story Source:

    The above story is reprinted from materials provided by Duke University. The original article was written by Richard Merritt.

    Note: Materials may be edited for content and length. For further information, please contact the source cited above.


    Journal Reference:

    1. Jianfeng Zang, Seunghwa Ryu, Nicola Pugno, Qiming Wang, Qing Tu, Markus J. Buehler, Xuanhe Zhao. Multifunctionality and control of the crumpling and unfolding of large-area graphene. Nature Materials, 2013; DOI: 10.1038/nmat3542

    Note: If no author is given, the source is cited instead.

    Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

    Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/OvIiUOFjQuc/130123165042.htm

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    Success with BlackBerry ?diehards? isn?t the key to BlackBerry 10?s future

    BlackBerry 10 Launch AnalysisBlackBerry 10

    Research In Motion (RIMM) shares are up more than 164% over the past six months as hype surrounding the struggling vendor?s next-generation BlackBerry 10 smartphone platform peaks. While the increased anticipation may lead to success in the early days for RIM?s new BlackBerry Z10 and BlackBerry X10 smartphones, the company has a much steeper mountain to climb if it hopes to compete in the cutthroat smartphone market.?RBC Capital Markets analyst Mark Sue is trying to keep a level head amid the buzz, and he paints a realistic picture of RIM?s prospects in 2013.

    [More from BGR: BlackBerry 10 browser smokes iOS 6 and Windows Phone 8 in comparison test [video]]

    In a note to investors on Wednesday, Sue raised his price target on RIM shares to $19, up from $11, with a?Sector Perform rating. He sees plenty of potential in BlackBerry 10, but he also warns clients that industry watchers may be getting sucked into the hype and are issuing overzealous estimates as a result.

    [More from BGR: Leaked pictures show HTC?s cleaned-up Sense interface from the upcoming M7]

    Though some are calling for RIM to sell as many as 30 million handsets to current BlackBerry users, Sue says converting the ?diehards? it just the beginning and convincing the bulk of RIM?s current installed base won?t be as easy as many believe.

    ?Our forecast calls for RIM to ship 500k BB10 units in the Feb-quarter and 10M in CY13,? the analyst wrote. ?Heavy subsidies and promotions may be required to sustain initially positive trends. Approximately 10?20M of RIM?s 79M installed base may upgrade to BB10 over time, although migration to low-cost Android is likely to continue. BB10, which does not entail mandatory service fees, will increase RIM?s mix of hardware revenue over time. Sustainable hardware margins have been elusive for many vendors.?

    Sue continued, noting that the stage is set for RIM?s early success with BlackBerry 10. He lists several things working in RIM?s favor, including 70,000 BlackBerry 10 apps available at launch, the fact that more than 1,600 businesses in North America are testing the platform, and the presence of several key points of differentiation in RIM?s new OS, such as BBM and the separation of work and personal profiles.

    But solid early BlackBerry 10 performance is only the tip of the iceberg for RIM.

    ?The true measure of success will be not just units, but also sustainable profitability, and competition is cut-throat with Windows convinced they will be the third mobile OS vendor,? Sue wrote. ?Heavy upfront spending may be required for the launch and we expect initially $500+ ASP and 10?15% gross margins on BB10 before volumes help margins.?

    This article was originally published on BGR.com

    Source: http://news.yahoo.com/success-blackberry-diehards-isn-t-key-blackberry-10-151528599.html

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